Permutation p-value approximation
In this PhD project, I develop an approach for accurate p-value approximation in permutation testing using the GPD (Generalized Pareto Distribution) while strictly avoiding zero p-values. The proposed p-value approximation framework, including precise fitting of GPD parameters, tail threshold detection, and multiple testing adjustment, will be made available in the open-source R package permAprox on GitHub and CRAN.'
The project is carried out under the supervision of Anne-Laure Boulesteix and Christian L. Müller, as well as in collaboration with the group of Prof.Dr. Erika von Mutius at the Helmholtz Zentrum München.
Stefanie Peschel
PhD candidate in Biostatistics
My research interests include microbiome data, network analysis, permutation tests, and R package development.
